![]() ![]() When differentiating in the direction of osteogenesis, oBMSCs and pBMSCs have shown a clearer osteogenic potential. In the adhesion assay, hBMSCs were significantly better than oBMSCs and pBMSCs. The migration assay showed significant differences between hBMSCs and pBMSCs and oBMSCs-up to 30 min, hBMSCs were faster than both types and after 60 min faster than pBMSCs. The oBMSCs exhibited a significantly higher doubling time than hBMSCs from passage 7. There was no significant difference between hBMSCs and pBMSCs in terms of self-renewal potential or growth potential. The cells from these three species were examined for their self-renewal potential proliferation potential adhesion and migration capacity adipogenic, osteogenic and chondrogenic differentiation potential and cell morphology. Hence, the aim of this study was to compare human-bone-marrow-derived mesenchymal stem cells (hBMSCs) with those from sheep (oBMSCs) and pigs (pBMSCs). For research and clinical use of stem cells, a suitable animal model is necessary.
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